Corrigendum: Serotonin Deficiency Exacerbates Acetaminophen-Induced Liver Toxicity In Mice
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منابع مشابه
Serotonin Deficiency Exacerbates Acetaminophen-Induced Liver Toxicity In Mice
Acetaminophen (APAP) overdose is a major cause of acute liver failure. Peripheral 5-hydroxytryptamine (serotonin, 5-HT) is a cytoprotective neurotransmitter which is also involved in the hepatic physiological and pathological process. This study seeks to investigate the mechanisms involved in APAP-induced hepatotoxicity, as well as the role of 5-HT in the liver's response to APAP toxicity. We i...
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Polyphenolics form a major part of the dietary antioxidant capacity of fruits and vegetables have been identified as chemopreventive or anticancer agents. Hydroxychalcones are polyphenols abundantly distributed throughout the plant kingdom and are compounds with two aromatic rings (benzene or phenol) and an unsaturated side chain. In the present study, effect of phloretin (apple major fl...
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Acetaminophen (APAP) toxicity threatens human health due to increased mortality associated with its overdose. Doxycycline (DC) because of its properties such as antioxidant and anti-inflammatory can be a good therapeutic strategy to treat the acute toxicity induced by APAP. Male mice were divided to six groups in two periods of 3 and 24-h as normal saline, APAP 400 mg/kg, DC 100 mg/kg and group...
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متن کاملمصرف خوراکی عصاره استویا کاهش دهنده عوارض کبدی و عصبی القا شده توسط استامینوفن در موش کوچک
Introdution: Oral consumption of Stevia extract increased the antioxidants' level in the body. In this study, the effect of Stevia extract consumption was investigated against neurological and liver complications caused by acute and chronic toxicity of acetaminophen administration in mice. Methods: In acute experiment, NMRI mice (n=12) received stevia extract (400 mg/ml) in drinking water for ...
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عنوان ژورنال:
دوره 5 شماره
صفحات -
تاریخ انتشار 2015